HIP1R Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 168141AP
DescriptionHuntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|HIP 12, HIP1 related protein, HIP12, HIP1R, HIP3, ILWEQ, KIAA0655|
|29816, 81917, 9026|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|HIP1R Fusion Protein Ag10353|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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