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HIRA Mouse anti-Human, Mouse, Clone: WC119.2H11, Active Motif™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen HIRA
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2720 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39558
10 μg
Each for $135.30
Add to cart
 
50-199-2719 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39557
100 μg
Each for $534.00
Add to cart
 
Description

Description

HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Specifications

Specifications

Monoclonal
Primary
HIRA
Unconjugated
SDS
Product Certifications
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