Histone H2A.Z Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA588544

Catalog No. PIPA588544

Description

Immunogen sequence: MAGGKAGKDS GKAKTKAVSR SQRAGLQFPV GRIHRHLKSR TTSHGRVGAT AAVYSAAILE YLTAEVLELA GNASKDLKVK RITPRHLQLA IRGDEELDSL IKATIAGGGV IPHIHKSLIG KKGQQKTV; Positive Samples: HL-60, MCF-7, 22Rv1, PC-12, HepG2, Mouse testis, Mouse thymus; Cellular Location: Chromosome, Nucleus

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene.

Specifications

• Antigen: Histone H2A.Z
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2AFZ
• Gene Symbols: H2AFZ
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFZ
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunofluorescence, Western Blot
• Concentration: 3.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P0C0S5, P0C0S6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3015, 51788
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid