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Histone H3ac (pan-acetyl) Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 39139

Encompass

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Catalog No. 50-199-3907


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Description

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Histone H3ac (pan-acetyl)
Conc. Not Determined
whole serum with 30% glycerol and 0.035% sodium azide; pH
Rabbit
IgG
RUO
Antibody
Polyclonal
ChIP assay, ChIP-sequencing, Dot Blot, Western Blot
Unconjugated
Liquid
This Histone H3 acetyl antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of histone H3.
100 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
Human
SDS
Documents
Product Certifications
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