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Histone H3K27me2me3 Mouse anti-Human, Clone: 7B11, Active Motif™

Mouse Monoclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 39538

Encompass

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Catalog No. 50-199-2711


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Description

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Histone H3K27me2me3
7B11
Unconjugated
Liquid
This Histone H3 di/trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3.
Protein A
RUO
Antibody
Monoclonal
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5
Mouse
IgG
10 μg
-20°C, Avoid Freeze/Thaw Cycles
Primary
Human
SDS
Documents
Product Certifications
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