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Histone H3R17me2aK18ac Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 61613

Encompass

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Catalog No. 50-199-3550


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Description

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Histone H3R17me2aK18ac
ChIP assay, Dot Blot, Western Blot
Unconjugated
H3F3B
Liquid
This antibody was raised against a synthetic peptide containing asymmetric dimethyl arginine 17 and acetyl lysine 18 of human Histone H3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
H3F3A, H3F3B
Lot-Specific
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
P84244
Rabbit
IgG
100 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
15078, 15081
SDS
Documents
Product Certifications
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