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Histone H3S28ph Mouse anti-Human, Clone: 5F9A9, Active Motif™

Mouse Monoclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 61695

Encompass

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Catalog No. 50-199-3626


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Description

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Histone H3S28ph
5F9A9
Unconjugated
Liquid
This antibody was raised against a peptide corresponding to phospho-serine 28 of human Histone H3.
Protein A
RUO
Antibody
Monoclonal
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Mouse
IgG2b
100 μg
-20°C, Avoid Freeze/Thaw Cycles
Primary
Human
SDS
Documents
Product Certifications
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