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Cytiva HiTrap™ MabSelect™ Prepacked Columns PROMO

Cytiva HiTrap™ MabSelect™ Prepacked Columns PROMO for small-scale MAb purification in a continuous bioprocess

Specifications

Binding Capacity ≈ 30mg Human lgG/mL at 2.4 min.
Diameter (English) Inner Column 0.62 in.
Diameter (Metric) Inner Column 1.6 cm
For Use With (Application) Fast purification of monoclonal antibodies from large sample volumes, Protein Purification
Sample Volume 5 mL
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Products 2
Catalog Number Mfr. No. Flow Rate Price Quantity & Availability  
Catalog Number Mfr. No. Flow Rate Price Quantity & Availability  
45-001-464LR0
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Cytiva
29489308
< 20 mL/min. This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. View substitute products »
45-001-467LR0
View Documents
Cytiva
29489309
< 4 mL/min. This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. View substitute products »
Description

Description

Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.

  • Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
  • High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
  • Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
  • Designed for use with a syringe, a peristaltic pump, or a chromatography system

MabSelect

  • Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
  • Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
MabSelect Xtra™
  • Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
  • Allows binding from samples with high expression levels of the monoclonal antibody
  • Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
MabSelect SuRe™ (Superior Resistance)
  • Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
  • Permits significant cost savings and extension of cycles in regular production

Specifications

Specifications

≈ 30mg Human lgG/mL at 2.4 min.
1.6 cm
5 mL
0.62 in.
Fast purification of monoclonal antibodies from large sample volumes, Protein Purification
20% Ethanol
SDS
Product Certifications
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