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Cytiva HiTrap™ MabSelect SuRe™ PCC Columns

Prepacked with MabSelect SuRe™ PCC Protein A Resin for screening and small-scale mAb purification in continuous bioprocessing using periodic counter-current chromatography (PCC)

Supplier:  Cytiva 17549112

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Catalog No. 09-928-121


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Description

Description

  • Suited for small scale antibody purifications, as well as optimization of methods and parameters, such as sample load and protein binding conditions
  • Alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols
  • These protein A columns provide fast, reproducible, and easy separations in a convenient format
  • Highly concentrated elution pools for operating flexibility and small unit operations
  • Allows cost-effective cleaning with 0.1 to 0.5 M NaOH over hundreds of purification cycles
  • Efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result
  • Columns are optimally utilized when they are connected to liquid chromatography systems such as the ÄKTA systems
  • High binding capacity: ∼ 60 mg Human IgG/mL Resin at 2.4 min residence time
Specifications

Specifications

Flow Velocity: ≤ 600 cm/h
5 mL
1/Pk.
<20 mL/min
Store at 2°C to 8°C, 20% Ethanol
Affinity Column
MabSelect SuRe PCC Protein A Resin
Chromatography Column
16 mm
25 mm
5 bar (0.5 MPa)
∼60 mg Human IgG/mL Resin
Antibody Affinity Chromatography
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