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HLA DRA Mouse, Clone: 169-1B5.2, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2477220.1MG
Description
HLA DRA Monoclonal specifically detects HLA DRA in Human, Bovine, Feline samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence, CyTOF-ready.Specifications
| HLA DRA | |
| Monoclonal | |
| 1.0 mg/mL | |
| Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready | |
| FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
| IgG2b κ |
| Flow Cytometry, Immunofluorescence, CyTOF | |
| 169-1B5.2 | |
| Unconjugated | |
| PBS with No Preservative | |
| HLA-DRA | |
| Human peripheral blood leukocytes | |
| 0.1 mg | |
| Adaptive Immunity, Cell Biology, Diabetes Research, Immunology | |
| 3122 | |
| Human, Bovine, Feline | |
| Purified |
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