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HLA DRA Mouse, Clone: 169-1B5.2, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2477220.1MG
SDSDocumentsProduct Certifications Promotions
DescriptionHLA DRA Monoclonal specifically detects HLA DRA in Human, Bovine, Feline samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence, CyTOF-ready.
|Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready|
|FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW|
|Protein A or G purified|
|This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|Flow Cytometry, Immunofluorescence, CyTOF|
|PBS with No Preservative|
|Human peripheral blood leukocytes|
|Adaptive Immunity, Cell Biology, Diabetes Research, Immunology|
|Human, Bovine, Feline|
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