HLA DRA Mouse, Clone: 169-1B5.2, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2477220.2MG

Catalog No. NBP247722B

Description

HLA DRA Monoclonal antibody specifically detects Antigen in Bovine, Feline, Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: HLA DRA
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
• Gene Alias: FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2b κ

• Applications: Flow Cytometry, Immunofluorescence, CyTOF
• Clone: 169-1B5.2
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: HLA-DRA
• Immunogen: Human peripheral blood leukocytes
• Quantity: 0.2 mg
• Research Discipline: Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
• Gene ID (Entrez): 3122
• Target Species: Human, Bovine, Feline
• Form: Purified