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HMGB2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549720

Catalog No. PA549720


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Description

Description

The antibody detects endogenous level of total HMGB2 protein.

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Specifications

Specifications

HMGB2
Polyclonal
Unconjugated
HMGB2
Liquid
HMGB2
Synthetic peptide corresponding to a region derived from 166-180 amino acids of Human high mobility group box 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ELISA, Western Blot
0.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P26583, P30681
HMG2
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3148, 97165
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