HMGB2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549720
The antibody detects endogenous level of total HMGB2 protein.HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
|Synthetic peptide corresponding to a region derived from 166-180 amino acids of Human high mobility group box 2|
|Antigen affinity chromatography|
|ELISA, Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|-20° C, Avoid Freeze/Thaw Cycles|
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