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HMGN1 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen HMGN1
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2890 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39834
10 μL
Each for $135.30
Add to cart
 
50-199-2889 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39833
100 μL
Each for $534.00
Add to cart
 
Description

Description

The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates. HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence. Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber. In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development.
Specifications

Specifications

Polyclonal
Primary
HMGN1
Unconjugated
SDS
Product Certifications
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