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HMGN3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551183

Catalog No. PA551183


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Description

Description

The antibody detects endogenous levels of total HMGN3 protein.

Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
Specifications

Specifications

HMGN3
Polyclonal
Unconjugated
HMGN3
Liquid
HMGN3
Full length fusion protein of human HMGN3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Western Blot
1.3 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q15651, Q9DCB1
TRIP7, PNAS-24, PNAS-25
Rabbit
IgG
100 μL
-20°C
Primary
9324, 94353
Documents
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