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HMGN3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548798

Catalog No. PA548798

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Predicted to react with bovine and mouse based on sequence homology.

Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
Specifications

Specifications

HMGN3
Polyclonal
PBS with 0.09% sodium azide
Q15651
High mobility group nucleosome-binding domain-containing protein 3, Thyroid receptor-interacting protein 7, TR-interacting protein 7, TRIP-7, HMGN3, TRIP7
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9324
Western Blot
Unconjugated
HMGN3
Liquid
HMGN3
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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