HNF1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 224261AP
DescriptionThis gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P15257, P20823, P22361|
|HNF 1 alpha, HNF 1A, HNF1, HNF1 homeobox A, HNF1A, LFB1, MODY3, TCF 1, TCF1, Transcription factor 1|
|21405, 24817, 6927|
|Immunoprecipitation, Western Blot|
|HNF1A Fusion Protein Ag18188|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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