Invitrogen™ hnRNP L Monoclonal Antibody (OTI9G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526733

Catalog No. PIMA526733

Description

hnRNP L Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: hnRNP L
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P14866, Q8R081
• Gene Symbols: HNRNPL
• Immunogen: Human recombinant protein fragment corresponding to amino acids 270-502 of HNRNPL produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI9G7
• Conjugate: Unconjugated
• Gene: HNRNPL
• Gene Alias: C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15388, 3191
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid