HOXB4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 222561AP
DescriptionHOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|homeobox B4, Homeobox protein Hox 2.6, Homeobox protein Hox 2F, Homeobox protein Hox B4, HOX 2.6, HOX2, HOX2F, HOXB4|
|HOXB4 Fusion Protein Ag17761|
|Antigen Affinity Chromatography|
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