HOXB7 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA548725
DescriptionThe homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most maligt T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis.
|PBS with 0.09% sodium azide|
|Homeobox protein Hox-B7, Homeobox protein Hox-23, Homeobox protein MH-22B, Homeobox protein MuB1, Hoxb7, Hox-23, Hoxb-7|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of mouse Hoxb7.|
|Antigen affinity chromatography|
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