HOXC10 Mouse anti-Human, Clone: OTI5C10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527065
DescriptionThe Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC10 oscillates in abundance during the cell cycle, being targeted for degradation early in mitosis by the ubiquitin-dependent proteasome pathway. HoxC10 is a homeoprotein with the potential to influence mitotic progression, and might provide a link between developmental regulation and cell cycle control.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HOX3I, homeo box C10, homeobox protein Hox-3I, homeobox protein Hox-C10, homeoprotein C10|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 1-262 of HOXC10 produced in E.coli|
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