Invitrogen™ HOXD10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596759

Catalog No. PIPA596759

Description

Immunogen sequence: MSFPNSSPAA NTFLVDSLIS ACRSDSFYSS SASMYMPPPS ADMGTYGMQT CGLLPSLAKR EVNHQNMGMN VHPYIPQVDS WTDPNRSCRI EQPVTQQVPT CSFTTNIKEE SNCCMYSDKR NKLISAEVPS YQRLVPESCP VENPEVPVPG YFRLSQTYAT GKTQEYNNSP EGSSTVMLQL NPRGAAKPQL SAAQLQMEKK MNEPVSGQEP TKVSQVESPE AKGGLPEERS CLAEVSVSSP; Positive Samples: Mouse kidney, Mouse heart, Rat heart; Cellular Location: Nucleus.

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Specifications

• Antigen: HOXD10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXD10
• Gene Alias: AI385591; AI874987; d10; homeo box 4D; homeo box D10; homeo box D10a; homeobox D10; homeobox D10a; homeobox gene D-10; homeobox protein Hox-4.5; Homeobox protein Hox-4D; homeobox protein Hox-4E; Homeobox protein Hox-5.3; homeobox protein Hox-C10; Homeobox protein Hox-D10; homeobox protein Hox-D10a; homeobox protein Hox-D11; homeobox protein Hox-D10; HOX4; Hox-4.4; Hox-4.5; Hox-45; HOX4D; HOX4E; Hox-5.3; hoxc10; hox-C10; Hoxc10 protein; Hoxd10; HOX-D10; hoxd-10; hoxd10a; hoxd10a protein; z-82
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15430, 303991, 3236
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.63 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P28358, P28359
• Gene Symbols: HOXD10
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HOXD10 (NP_0021392).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG