HOXD8 Mouse anti-Human, Clone: OTI2A1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527377
DescriptionThe Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HOX4, HOX4E, HOX5.4, Hox-4.5, homeo box 4E, homeo box D8, homeobox protein 5.4, homeobox protein Hox-4E, homeobox protein Hox-5.4, homeobox protein Hox-D8|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 69-290 of HOXD8 produced in E.coli|
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