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HSC70 / HSP7C Rat anti-Human, Clone: 60, Active Motif™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$116.85 - $356.95

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen HSC70 / HSP7C
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3238 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61208
10 μg
Each for $116.85
Add to cart
 
50-199-3237 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61207
100 μg
Each for $356.95
Add to cart
 
Description

Description

The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria. HSC70 (also known as HSC71, HSC73, HSP73, p72, prp73) is expressed constitutively and is slightly heat-inducible. HSC70 binds to the exposed loop of clathrin light chains to promote uncoating and can also bind the cytoskeleton which may facilitate cytoskeletal rearrangements. HSC70 has been shown to stimulate lysosomal degradation of intracellular proteins and to retard both aggregation and folding of mitochondrial precursor proteins in vitro.
Specifications

Specifications

Monoclonal
Primary
HSC70 / HSP7C
Unconjugated
SDS
Product Certifications
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