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HSF1 Rat anti-Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey, Clone: 10H8, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA527688

Catalog No. PIMA527688


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Description

Description

Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
Specifications

Specifications

HSF1
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
P38532, Q00613, Q08DJ8
HSTF1, Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1
Rat
IgG1
100 μg
-20°C
Primary
100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
10H8
Unconjugated
HSF1
Liquid
Hsf1
Purified recombit mouse HSF1 protein, with epitope mapping to amino acids 378-395
Protein G
RUO
Antibody
Monoclonal
Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Documents
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