HSF1 Rat anti-Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey, Clone: 10H8, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA527688
DescriptionHeat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|P38532, Q00613, Q08DJ8|
|HSTF1, Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1|
|100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Purified recombit mouse HSF1 protein, with epitope mapping to amino acids 378-395|
|Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey|
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