HSP27 Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
PIPA126358	50 μg

Catalog No. PIPA126358

Supplier: Thermo Scientific PA126358

Description

Rabbit Polyclonal Antibody

PA1-26358 detects Heat Shock Protein 27 from human and monkey samples. PA1-26358 has been successfully used in immunoprecipitation, immunocyctochemistry, ELISA and Western blot procedures. The PA1-26358 immunogen is recombit human Heat Shock Protein 27 protein. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Heat shock proteins (HSP) are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs including HSP70, HSP90 and HSP100. HSP27 also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP′s and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that HSP27 may be a useful marker in classifying various hormone sensitive tumors.

Specifications

• Antigen: HSP27
• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Gene: HSPB1
• Gene Accession No.: P04792
• Gene Alias: Heat shock protein beta-1; HspB1; HSP25; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27; Estrogen-regulated 24 kDa protein; 28 kDa heat shock protein; HSPB1; HSP27
• Gene Symbols: HSPB1
• Host Species: Rabbit
• Immunogen: Recombit human Heat Shock Protein 27 protein.
• Purification Method: Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3315
• Target Species: Human, Non-human Primate
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG