HSP60 Antibody (LK2), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234671AF350

Catalog No. NB006312

Description

HSP60 Monoclonal specifically detects HSP60 in Human, Mouse, Rat, Bacteria, Chicken, E. coli, Guinea Pig, Hamster, Invertebrate, Parasite, Plant, Monkey, Yeast samples. It is validated for Immunohistochemistry-Paraffin.

Specifications

• Antigen: HSP60
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: HSPD1
• Immunogen: Recombinant human HSP60 protein (Uniprot: P10809 )
• Quantity: 0.1 mL
• Research Discipline: Apoptosis, Cellular Markers, Loading Controls, Membrane Trafficking and Chaperones, Mitochondrial Markers
• Test Specificity: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). Its epitope is localized between aa 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: LK2
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Alias: 60 kDa chaperonin, Chaperonin 60, CPN60, GROEL, heat shock 60kD protein 1 (chaperonin), heat shock 60kDa protein 1 (chaperonin), Heat shock protein 60, heat shock protein 65, HLD4, Hsp60, HSP-60, HSP60SPG13, HSP65, HuCHA60, Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial, P60 lymphocyte protein, short heat shock protein 60 Hsp60s1, spastic paraplegia 13 (autosomal dominant)
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bacteria, Chicken, Fungi, Guinea Pig, Hamster, Parasite, Primate, Yeast
• Isotype: IgG1 κ