HSPA5 Mouse anti-Human, Rat, Clone:9E4-2A7-H6, Abnova
Mouse monoclonal antibody raised against recombinant human HSPA5.
Manufacturer: Abnova Corporation MAB17662
DescriptionWhen Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as ft.immunoglobulin heavy chain-binding protein ft. (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
|heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)|
|In PBS, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody detects endogenous levels of HSPA5 and does not cross-react with related proteins.|
|Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot|
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
|BIP, FLJ26106, GRP78, MIF2|
|Recombinant protein corresponding to a fragment at C-terminus of human HSPA5 from E. coli.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok