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HSPB8 Mouse anti-Human, Rat, Clone: OTI1E3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525112

Catalog No. PIMA525112


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Description

Description

Crystallins are the major proteins expressed in the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b and g families; b and g-crystallins compose a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. a-crystallins consist of three gene products, aA, aB and aC-crystallin, which are members of the small heat shock protein family (HSP20). They are induced by heat shock, and act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, a-crystallins do not renature these proteins. Research indicates that binding occurs between membranes and aC-crystallin. The binding site appears to be at the polar-apolar interface in membrane protein (MIP26) and aC-crystallin; the lipid bilayer becomes less mobile with aC-crystallin binding.
Specifications

Specifications

HSPB8
Monoclonal
0.88 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UJY1, Q9EPX0
Alpha crystallin C chain; Alpha-crystallin C chain; Charcot Marie Tooth disease axonal type 2L; Charcot Marie Tooth disease spinal; CMT2L; CRYAC; DHMN 2; DHMN2; E2 induced gene 1 protein; E2-induced gene 1 protein; E2IG1; H11; Heat shock 22kDa protein 8; Heat shock 27kDa protein 8; Heat shock protein 22; Heat shock protein beta 8; Heat shock protein beta-8; Hereditary motor neuropathy distal; HMN 2; HMN2; HMN2A; HSB8; HSPB 8; Hspb8; HSPB8_HUMAN; OTTHUMP00000239768; Protein kinase H11; Small stress protein like protein HSP22; Small stress protein-like protein HSP22; Spinal muscular atrophy distal adult autosomal domit;
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
113906, 26353
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1E3
Unconjugated
HSPB8
Liquid
HSPB8
Full length human recombit protein of HSPB8 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Rat
Documents
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