Invitrogen™ HSPE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530428

Catalog No. PIPA530428

Description

Recommended positive controls: mouse brain. Predicted reactivity: Mouse (96%), Rat (98%), Zebrafish (82%), Japanese Medaka (86%), Xenopus laevis (88%), Pig (100%), Chicken (87%), Rhesus Monkey (99%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The low molecular weight family includes HSP 10, HSP 20, HSP 27 (Heme Oxygenase 1), HSP 32 and HSP 40. Chaperonins are ubiquitous, indispensable proteins that facilitate protein folding in an ATP-dependent manner, enhancing the yield of properly folded substrate protein under conditions where spontaneous folding does not occur. Chaperonins are typified by the E. coli heat-shock proteins GroEL and GroES (HSP 10). HSP 10 is a heptameric ring of identical 10 kDa subunits that binds to each end of GroEL to form a symmetric, functional heterodimer.

Specifications

• Antigen: HSPE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPE1
• Gene Alias: 10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; 10 kDa heat shock protein, mitochondrial; MOB-like protein phocein; 10kDa; 10kDa Chaperonin; CH10; chaperonin 10; Cpn 10; CPN10; cpn10 protein; early pregnancy factor; early-pregnancy factor; EPF; GROES; Heat shock 10 kD protein 1 (chaperonin 10); heat shock 10 kDa protein 1 (chaperonin 10); heat shock 10 protein 1; heat shock 105kDa/110kDa protein 1; heat shock 10kD protein; heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; heat shock 10kDa protein 1 (chaperonin 10); heat shock protein; heat shock protein 1 (chaperonin 10); heat shock protein 105; heat shock protein 105 kDa; heat shock protein 105 kDa; LOW QUALITY PROTEIN: heat shock protein 105 kDa; heat shock protein family E (Hsp10) member 1; heat shock protein family E (Hsp10) member 1 L homeolog; heat shock protein family H (Hsp110) member 1; HSP; hsp10; hsp105; hsp105a; hsp105b; hsp110; Hspe1; hspe1.L; Hsph1; hsph1-a; hsph1-b; mitochondrial 10 kDa heat shock protein; mitochondrial chaperonin 10; MOB family member 4, phocein; MOB1, Mps One Binder kinase activator-like 3; MOB4; MOBKL3; mob-like protein phocein; mt-cpn10; PREI3; preimplantation protein 3; XELAEV_18045050mg; zgc:86747
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15528, 3336
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P61604, Q64433
• Gene Symbols: HSPE1
• Immunogen: Full length human Cpn10 Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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