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Platelet GPVI Mouse anti-Human, PE, Clone: HY101, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565241

Catalog No. BDB565241

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The HY101 monoclonal antibody specifically binds to a collagen receptor, Platelet Glycoprotein VI (GPVI or GP6). GPVI is a 58-kD platelet membrane glycoprotein that belongs to the immunoglobulin superfamily. Upon blood vessel wall injury and consequent endothelial cell damage, platelets collect upon the exposed collagen fibers present in the subendothelial matrix. The platelet and collagen interaction leads to activated platelet aggregation and thrombus formation. Although normally serving a protective function in clot formation that limits blood loss, the platelet GPVI/collagen interaction may also play a role in myocardial infarction and stroke which are associated with the rupture of atherosclerotic plaques.



Platelet GPVI
Glycoprotein 6; GP6; Platelet glycoprotein VI; Platelet collagen receptor
Affinity purified
Glycoprotein VI Recombinant Protein
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
IgG1, κ
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