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R&D Systems™ Human Active MMP-9 Fluorokine E Kit, R&D Systems™ Available on GSA/VA Contract for Federal Government customers only.

For the quantitative determination of human active Matrix Metalloproteinase 9 (MMP-9) in cell culture supernates, serum, plasma, and urine.

Manufacturer:  R&D Systems™ F9M00

Catalog No. F9M00

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The Fluorokine™ E Human Active MMP-9 Florescent Assay combines the specificity of a monoclonal antibody that captures all three MMP-9 forms (92, 82, and 65 kDa) but not other MMPs and the sensitivity of fluorescence. The assay is designed to measure the levels of endogenous human active MMP-9 in cell culture supernates, serum, plasma, and urine and the MMP-9 in these samples that can be activated by APMA during the assay procedure. The determined MMP-9 activity may reflect the balance of MMP-9 and its inhibitor TIMPs. Therefore, it is recommended that the levels of TIMPs be determined in order to interpret the results properly. For example, TIMP-1 inhibits the activity of MMP-9 through binding of the N-terminal domain of the TIMP-1 to the active site of MMP-9. In addition, TIMP-1 also binds to pro-MMP-9 through the interaction between the C-terminal domains of both proteins .

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0.25 - 16pg/mL
Store the unopened product at 2° to 8°C. Do not use past expiration date.
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