Abnova™ Human ALDH3A1 (AAH04370, 1 a.a. - 453 a.a.) Full-length Recombinant Protein with His tag

Used for Func, SDS-PAGE

Supplier:  Abnova™ P3496

Catalog No. 89-933-108

Description

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Sequence: MGSSHHHHHHSSGLVPRGSHMSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH

Specifications

• Accession Number: AAH04370
• For Use With (Application): Functional Study, SDS-PAGE
• Gene ID (Entrez): 218
• Name: ALDH3A1 (Human) Recombinant Protein
• Purification Method: Conventional Chromatography
• Quantity: 50 ug
• Regulatory Status: RUO
• Common Name: ALDH3A1
• Biological Activity: Specific activity is < 1 units/mL and was obtained by measuring the increase of NADP in absorbance at 340nm resulting from the reduction of NAD. One unit will oxidize 1.0μmole of acetaldehyde to acetic acid per minute at pH 8.0 at 25°C in the pre
• Recombinant: Recombinant
• Expression System: Escherichia coli expression system
• Purity or Quality Grade: >95% by SDS-PAGE

• Concentration: 0.5 mg/mL
• Formulation: In 20mM Tris-HCl, 0.1M NaCl, pH 8.0 (10% glycerol)
• Molecular Weight (g/mol): 52.5kDa
• Preparation Method: Escherichia coli expression system
• Quality Control Testing: Loading 3 ug protein in 15% SDS-PAGE
• Storage Requirements: Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
• Gene Alias: ALDH3/ALDHIII/MGC10406
• Gene Symbol: ALDH3A1
• Species: E. coli
• Protein Tag: His
• Form: Liquid