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Abnova™ Human AURKC (NP_002392.2, 1 a.a. - 275 a.a.) Full-length Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5686

Catalog No. 89-936-179


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Description

Description

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Specifications

Specifications

Baculovirus expression system
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
In 50mM Tris-HCl, 150mM NaCl, pH 7.5 (0.1% CHAPS, 1mM DTT, 10% glycerol)
59kDa
Baculovirus expression system
80% by SDS-PAGE/CBB staining
5 ug
RUO
AURKC
The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Kemptide. ATP: 100 µM.
Yes
NP_003151.2
Liquid
6795
AURKC (isoform 3) (Human) Recombinant Protein
Glutathione sepharose chromatography
Loading 1 ug protein in SDS-PAGE
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
AIE2/AIK3/AurC/STK13/aurora-C
AURKC
Insect
GST
SDS
Documents
Product Certifications
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