Invitrogen™ Human Brevican ELISA Kit
Human Brevican quantitates human Brevican in serum, plasma, supernatant.
Manufacturer: Invitrogen™ EH52RB
Human Brevican quantitates human Brevican in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Brevican.Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
|Colorimetric Microplate Reader|
|Research Use Only|
|2°C to 8°C|
|4 hr 45 min|
|ALPBRE; Bcan; BEHAB; Brain-enriched hyaluronan-binding protein; brevican; brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; Chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; CSPG7; UNQ2525/PRO6018|
|0.041 to 10 ng/mL|
|Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|Serum, 50 µL; Plasma, 50 µL; Supernatant, 50 µL|
|1 hr 20 min|
|Serum, Plasma, Supernatant|
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