Invitrogen™ Human ACE2 (aa1-615) Fc Chimera Recombinant Protein

HEK293 cells Recombinant Protein

Supplier:  Invitrogen™ RP87692

Catalog No. PIRP87692

Description

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Specifications

• Accession Number: Q9BYF1
• For Use With (Application): Control, ELISA, Western Blot
• Gene ID (Entrez): 59272
• Quantity: 200 μg
• Storage Requirements: -20°Cor to +80°C if preferred
• Gene Alias: 2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885
• Specific Reactivity: Human
• Recombinant: Recombinant
• Purity or Quality Grade: >95%

• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Name: Human ACE2 (aa1-615) Fc Chimera
• Source: HEK293 cells
• Regulatory Status: RUO
• Gene Symbol: ACE2
• Conjugate: Unconjugated
• Form: Lyophilized