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Abnova™ Human CSF1R (NP_005202.2, 538 a.a. - 972 a.a.) Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5715

Catalog No. 89-940-695


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Description

Description

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq]

Specifications

Specifications

NP_005202.2
Liquid
1436
CSF1R (Human) Recombinant Protein
Glutathione sepharose chromatography
Loading 1 ug protein in SDS-PAGE
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
C-FMS|CD115|CSFR|FIM2|FMS
CSF1R
The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Srctide. ATP: 100 µM.
Yes
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
76kDa
Baculovirus infected insect cell (Sf21) expression system
77% by SDS-PAGE/CBB staining.
5 ug
RUO
CSF1R
Baculovirus infected insect cell (Sf21) expression system
Insect
GST
Documents
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