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Abnova™ Human DDR2 (NP_001014796.1, 467 a.a. - end) Partial Recombinant Protein expressed in Sf9 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4242

Catalog No. 89-941-624


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Description

Description

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Specifications

Specifications

NP_001014796.1
Liquid
4921
DDR2 (Human) Recombinant Protein
≥90% by SDS-PAGE
5 ug
RUO
DDR2
Insect cell (Sf9) expression system
Insect
None
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
70kDa
Insect cell (Sf9) expression system
SDS-PAGE Result
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
MIG20a|NTRKR3|TKT|TYRO10
DDR2
The specific activity of DDR2 was determined to be 25nmol/min/mg as per activity assay protocol.
Yes
Documents
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