Abnova™ Human EGFR (NM_005228.3, 672 a.a. - 1210 a.a.) amino acids 746-750 deleted Partial Protein expressed in Sf9 cells

Used for Func, SDS-PAGE

Supplier:  Abnova™ P4815

Catalog No. 89-942-918

Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]

Sequence: HIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA

Specifications

• Accession Number: NM_005228.3
• For Use With (Application): Functional Study, SDS-PAGE
• Gene ID (Entrez): 1956
• Name: EGFR (d746-750) (Human) Recombinant Protein
• Purification Method: GST affinity chromatography
• Quantity: 100 ug
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Gene Alias: ERBB/ERBB1/HER1/PIG61/mENA
• Gene Symbol: EGFR
• Species: Baculovirus
• Expression System: Insect cell (Sf9) expression system

• Concentration: 0.096 ug/uL
• Formulation: Liquid
• Molecular Weight (g/mol): 88.572kDa
• Preparation Method: Insect cell (Sf9) expression system
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Immunogen: HIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
• Regulatory Status: RUO
• Common Name: EGFR
• Biological Activity: 20pmol/μg x min
• Protein Tag: None
• Form: Liquid