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Invitrogen IL-4 Human Uncoated ELISA Kit with Plates
Specifically engineered for accurate and precise measurement of human IL-4 protein levels from samples including serum, plasma, and cell culture supernatants.
Manufacturer: Invitrogen 88704686
DescriptionInterleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
|Plasma, Serum, Supernatant|
|Colorimetric Microplate Reader|
|2°C to 8°C|
|24 hr. 30 min.|
|10 x 96 Tests|
|10X Coating Buffer: Buffer for plating the Capture Antibody|
|Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL|
|1 hr. 45 min.|
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