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Abnova™ Human IL2RA (P01589) Partial Recombinant Protein expressed in Hi-5 Insect cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P6152

Catalog No. 89-948-868


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Description

Description

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. [provided by RefSeq]

Sequence: ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ
Specifications

Specifications

P01589
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Lyophilized
24.8kDa
Insect cell (Hi-5) expression system
25 ug
Store at -20°C. Reconstitute in 1x PBS pH 7.2 to a concentration of 0.1- 1.0 mg/mL. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
<0.1ng/μg of protein (<1 EU/μg).
IL2RA
Activity assay
SDS-PAGE
The optimal working dilution should be determined by the end user.
Human ;Human
Yes
Insect cell (Hi-5) expression system
Lyophilized
3559
IL2RA (Human) Recombinant protein
0.98
ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ
RUO
CD25|IDDM10|IL2R|TCGFR
IL2RA
Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1ng/mL of recombinant IL-2, the expected ED50 for this effect is between 0.5-1.5μg/mL.
Insect
None
Documents
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