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Abnova™ Human IL5 (P05113, 232 amino acids) Partial Recombinant Protein

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P3990

Catalog No. 89-948-926


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Description

Description

The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq]

Specifications

Specifications

P05113
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Lyophilized
26.5kDa
Escherichia coli expression system
10 ug
RUO
EDF|IL-5|TRF
IL5
Escherichia coli
None
Escherichia coli expression system
Lyophilized
3567
IL5 (Human) Recombinant Protein
≥98% by SDS-PAGE and HPLC
Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
<0.1ng/μg
IL5
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.15ng/mL, corresponding to a specific activity of > 6 x 106 units/mg.
Yes
Documents
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