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Abnova™ Human JAK2 (NP_004963.1, 532 a.a. - 1132 a.a.) V617F mutant Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5762

Catalog No. 89-949-401


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Description

Description

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq]

Specifications

Specifications

NP_004963.1
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
97kDa
Baculovirus infected insect cell (Sf21) expression system
74% by SDS-PAGE/CBB staining
5 ug
RUO
JAK2
The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Srctide. ATP: 100 µM.
Yes
Baculovirus infected insect cell (Sf21) expression system
Liquid
3717
JAK2 (V617F) (Human) Recombinant Protein
Glutathione sepharose chromatography
SDS-PAGE Stained with Coomassie Blue
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
JTK10
JAK2
Insect
GST
Documents
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