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Abnova™ Human JAK3 (NP_000206.2, 795 a.a. - 1124 a.a.) Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5724

Catalog No. 89-949-406


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Description

Description

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]

Specifications

Specifications

Baculovirus infected insect cell (Sf21) expression system
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
41kDa
Baculovirus infected insect cell (Sf21) expression system
83% by SDS-PAGE/CBB staining.
5 ug
RUO
JAK3
The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Srctide. ATP: 100 µM.
Yes
NP_000206.2
Liquid
3718
JAK3 (Human) Recombinant Protein
Glutathione sepharose chromatography
Loading 1 ug protein in SDS-PAGE
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK
JAK3
Insect
GST
Documents
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