Abnova™ Human KIT (NP_000213.1, 544 a.a. - 976 a.a.) V560G mutant Partial Recombinant Protein with GST-tag expressed in baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Supplier:  Abnova™ P5572

Catalog No. 89-949-949

Description

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Accession Number: NP_000213.1
• Formulation: Liquid
• Molecular Weight (g/mol): 76kDa
• Preparation Method: Baculovirus infected insect cell (Sf21) expression system
• Quality Control Testing: Loading 1 ug protein in SDS-PAGE
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Gene Alias: C-Kit/CD117/PBT/SCFR
• Gene Symbol: KIT
• Species: Baculovirus
• Protein Tag: GST
• Form: Liquid

• For Use With (Application): Functional Study, SDS-PAGE
• Gene ID (Entrez): 3815
• Name: KIT (V560G) (Human) Recombinant Protein
• Purification Method: Glutathione sepharose chromatography
• Quantity: 5 ug
• Regulatory Status: RUO
• Common Name: KIT
• Biological Activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: Srctide. ATP: 1000 uM
• Recombinant: Recombinant
• Expression System: Baculovirus infected insect cell (Sf21) expression system
• Purity or Quality Grade: 87% by SDS-PAGE/CBB staining