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Abnova™ Human LCK (NM_005356, 1 a.a. - 509 a.a.) Full-length Recombinant Protein with GST-His tag expressed in Sf9 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4714

Catalog No. 89-950-455


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Description

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq]

Specifications

Specifications

NM_005356
0.140 ug/uL
Liquid
3932
LCK (Human) Recombinant Protein
GST affinity chromatography
100 ug
RUO
LCK
66pmol/μg x min
Yes
Insect cell (Sf9) expression system
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
92.762kDa
Insect cell (Sf9) expression system
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Store at -80°C. Aliquot to avoid repeated freezing and thawing
YT16|p56lck|pp58lck
LCK
Insect
GST-His
Documents
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