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Abnova™ Human LEP (NP_002294.2, 1 a.a. - 839 a.a.) Partial Recombinant Protein with His tag

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4102

Catalog No. 89-950-551


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Description

Description

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq]

Specifications

Specifications

P41159
Lyophilized
3952
LEP (Human) Recombinant Protein
10 ug
RUO
LEP
Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
Yes
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Lyophilized
130-140kDa
≥98% by SDS-PAGE and HPLC
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
FLJ94114|OB|OBS
LEP
Escherichia coli
His
SDS
Documents
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