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Abnova™ Human MAP2K7 (NP_660186.1, 1 a.a. - 419 a.a.) K149M mutant Full-length Recombinant Protein with GST-tag

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5685

Catalog No. 89-951-610


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Description

Description

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq]

Specifications

Specifications

NP_660186.1
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
74kDa
Escherichia coli expression system
55% by SDS-PAGE/CBB staining
50 ug
RUO
MAP2K7
The activity was determined by ELISA. The enzyme was incubated with GST-fused substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into glutathione- coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG. Substrate: JNK1. ATP: 10 uM.
Yes
Escherichia coli expression system
Liquid
5609
MAP2K7 (K149M) (Human) Recombinant Protein
Glutathione sepharose chromatography
Loading 1 ug protein in SDS-PAGE
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Jnkk2|MAPKK7|MKK7|PRKMK7
MAP2K7
Escherichia coli
GST
SDS
Documents
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