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Abnova™ Human MAPK14 (NM_139012) Full-length Recombinant Protein with GST expressed in Sf9 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4239

Catalog No. 89-951-728


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Description

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Specifications

NM_139012
Liquid
1432
MAPK14 (Human) Recombinant Protein
SDS-PAGE Result
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA
MAPK14
Insect
GST
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Liquid
67kDa
≥90% by SDS-PAGE
5 ug
RUO
MAPK14
The specific activity of p38alpha was determined to be 77nmol/min/mg as per activity assay protocol.
Yes
SDS
Documents
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