Abnova™ Human MET (NP_000236.2, 956 a.a. - 1390 a.a.) Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P5728

Catalog No. 89-952-199

Description

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Accession Number: NP_000236.2
• For Use With (Application): Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
• Formulation: Liquid
• Molecular Weight: 76kDa
• Preparation Method: Baculovirus infected insect cell (Sf21) expression system
• Purity: 97% by SDS-PAGE/CBB staining.
• Quantity: 5 ug
• Regulatory Status: RUO
• Common Name: MET
• Biological Activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
  Substrate : Srctide. ATP: 100 µM.
• Recombinant: Yes

• Expression System: Baculovirus infected insect cell (Sf21) expression system
• Format: Liquid
• Gene ID (Entrez): 4233
• Name: MET (Human) Recombinant Protein
• Purification Method: Glutathione sepharose chromatography
• Quality Control Testing: Loading 1 ug protein in SDS-PAGE
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Gene Alias: AUTS9|HGFR|RCCP2|c-Met
• Gene Symbol: MET
• Host Species: Insect
• Protein Tag: GST